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Article

A small interfering RNA targeting Lnk accelerates bone fracture healing with early neovascularization.

Laboratory investigation; a journal of technical methods and pathology - 1 Sept 2013

Kawakami Yohei, Ii Masaaki, Matsumoto Tomoyuki, Kawamoto Atsuhiko, Kuroda Ryosuke, Akimaru Hiroshi, Mifune Yutaka, Shoji Taro, Fukui Tomoaki, Asahi Michio, Kurosaka Masahiro, Asahara Takayuki

Abstract excerpt

Lnk, an intracellular adapter protein, is expressed in hematopoietic cell lineages, which has recently been proved as an essential inhibitory signaling molecule for stem cell self-renewal in the stem cell factor-c-Kit signaling pathway with enhanced hematopoietic and osteogenic reconstitution in Lnk-deficient mice. Moreover, the therapeutic potential of hematopoietic stem/endothelial progenitor cells (EPCs) for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23897412
DOI: 10.1038/labinvest.2013.93

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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