Article
Nuclear fusion-independent smooth muscle differentiation of human adipose-derived stem cells induced by a smooth muscle environment.
Stem cells (Dayton, Ohio) - 1 Mar 2012
Zhang Rong, Jack Gregory S, Rao Nagesh, Zuk Patricia, Ignarro Louis J, Wu Benjamin, Rodríguez Larissa V
Abstract excerpt
Human adipose-derived stem cells hASC have been isolated and were shown to have multilineage differentiation capacity. Although both plasticity and cell fusion have been suggested as mechanisms for cell differentiation in vivo, the effect of the local in vivo environment on the differentiation of adipose-derived stem cells has not been evaluated. We previously reported the in vitro capacity of smooth muscle...
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