Article
Differentiation of adult stem cells into smooth muscle for vascular tissue engineering.
The Journal of surgical research - 15 Jun 2011
Harris Lisa J, Abdollahi Hamid, Zhang Ping, McIlhenny Stephen, Tulenko Thomas N, DiMuzio Paul J
Abstract excerpt
BACKGROUND: Herein we evaluate the potential of adipose-derived stem cells (ASC) to differentiate into smooth muscle cells (SMC) and their potential for use in a tissue-engineered vascular graft. MATERIALS AND METHODS: We isolated ASC (CD13+29+90+) from the peri-umbilical adipose tissue of patients undergoing vascular surgery, and cultured them in media containing angiotensin II (AngII),...
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