Article
The first two cases of neonatal alloimmune thrombocytopenia associated with the low-frequency platelet antigen HPA-21bw (Nos) in Japan.
Transfusion - 1 Jul 2012
Koh Yangsook, Ishii Hiroyuki, Amakishi Etsuko, Hayashi Tomoya, Matsuyama Nobuki, Fukumori Yasuo, Hirayama Fumiya, Shimizu Junji, Nakauchi Shohei, Kawa Keisei
Abstract excerpt
BACKGROUND: Neonatal alloimmune thrombocytopenia (NAIT) is a disorder characterized by maternal alloimmunization against paternal fetal platelet antigens. Two healthy, unrelated Japanese women each gave birth to a child with severe NAIT. STUDY DESIGN AND METHODS: To elucidate the maternal causes of NAIT, we conducted serologic and genetic studies in these two NAIT infants. RESULTS: The serologic experiments...
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