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Article

Genomic Sequencing of Key Genes in Mouse Pancreatic Cancer Cells

30 Jan 2012

Abstract excerpt

Pancreatic cancer is a multiple genetic disorder with many mutations identified during the progression. Two mouse pancreatic cancer cell lines were established which showed different phenotype in vivo: a non-metastatic cell line, Panc02, and a highly metastatic cell line, Panc02-H7, a derivative of Panc02. In order to investigate whether the genetic mutations of key genes in pancreatic cancer such as KRAS, TP53...

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PMID: 22208613
DOI: 10.2174/156652412799218868

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