Article
Correlation of activated STAT3 expression with clinicopathologic features in lung adenocarcinoma and squamous cell carcinoma.
Molecular diagnosis & therapy - 1 Dec 2011
Jiang Richeng, Jin Ziliang, Liu Zhujun, Sun Leina, Wang Liuchun, Li Kai
Abstract excerpt
BACKGROUND AND OBJECTIVE: Signal transducer and activator of transcription (STAT) 3, a member of the STAT family of transcription factors in the Janus kinase (JAK)/STAT signaling pathway, is involved in cell proliferation and apoptosis. STAT3 is activated through phosphorylation (p-STAT3) and is highly expressed in many malignancies. The aims of the present study were to evaluate STAT3 activation (p-STAT3 protein...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
