Article
A further study on chromosome minimization by protoplast fusion in Aspergillus oryzae.
Molecular genetics and genomics : MGG - 1 Feb 2012
Hara Seiichi, Jin Feng Jie, Takahashi Tadashi, Koyama Yasuji
Abstract excerpt
Our goal in this work was to develop a method to minimize the chromosomes of Aspergillus oryzae, to arrive at a deeper understanding of essential gene functions that will help create more efficient industrially useful strains. In a previous study, we successfully constructed a highly reduced chromosome 7 using multiple large-scale chromosomal deletions (Jin et al. in Mol Genet Genomics 283:1-12, 2010). Here, we...
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