A functional variant in ANGPT1 and the risk of pregnancies with hypertensive disorders and small-for-gestational-age infants.

doi:10.1093/molehr/gar081

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Article

A functional variant in ANGPT1 and the risk of pregnancies with hypertensive disorders and small-for-gestational-age infants.

Molecular human reproduction - 1 Jun 2012

Andraweera Prabha H, Dekker Gustaaf A, Thompson Steven D, North Robyn A, McCowan Lesley M E, Roberts Claire T

Abstract excerpt

Pregnancies complicated by pre-eclampsia and small-for-gestational-age (SGA) infants demonstrate impaired placental vascular remodelling. Angiopoietin-1 (ANG-1) is an angiogenic growth factor which regulates vascular integrity and remodelling. The TT genotype of angiopoietin 1 (ANGPT1) rs2507800 polymorphism has been associated with increased plasma ANG-1 levels compared with the AA genotype. We aimed to...

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PMID: 22205728
DOI: 10.1093/molehr/gar081

Genes

ANGPT1
ANG

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Source receipt: pubmed, retrieved 7 Sept 2026.

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