Article
Genetic polymorphisms associated with adverse pregnancy outcomes in nulliparas.
Scientific reports - 7 May 2024
Khan Raiyan R, Guerrero Rafael F, Wapner Ronald J, Hahn Matthew W, Raja Anita, Salleb-Aouissi Ansaf, Grobman William A, Simhan Hyagriv, Silver Robert M, Chung Judith H, Reddy Uma M, Radivojac Predrag, Pe'er Itsik, Haas David M
Abstract excerpt
Adverse pregnancy outcomes (APOs) affect a large proportion of pregnancies and represent an important cause of morbidity and mortality worldwide. Yet the pathophysiology of APOs is poorly understood, limiting our ability to prevent and treat these conditions. To search for genetic markers of maternal risk for four APOs, we performed multi-ancestry genome-wide association studies (GWAS) for pregnancy loss,...
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