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Article

The structure of allelic diversity in the presence of purifying selection.

Theoretical population biology - 1 Mar 2012

Desai Michael M, Nicolaisen Lauren E, Walczak Aleksandra M, Plotkin Joshua B

Abstract excerpt

In the absence of selection, the structure of equilibrium allelic diversity is described by the elegant sampling formula of Ewens. This formula has helped to shape our expectations of empirical patterns of molecular variation. Along with coalescent theory, it provides statistical techniques for rejecting the null model of neutrality. However, we still do not fully understand the statistics of the allelic...

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Identifiers

PMID: 22198521
DOI: 10.1016/j.tpb.2011.12.002
PMCID: PMC3671953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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