Article
Branched chain fatty acids reduce the incidence of necrotizing enterocolitis and alter gastrointestinal microbial ecology in a neonatal rat model.
PloS one - 1 Jan 2011
Ran-Ressler Rinat R, Khailova Ludmila, Arganbright Kelly M, Adkins-Rieck Camille K, Jouni Zeina E, Koren Omry, Ley Ruth E, Brenna J Thomas, Dvorak Bohuslav
Abstract excerpt
INTRODUCTION: Branched chain fatty acids (BCFA) are found in the normal term human newborn's gut, deposited as major components of vernix caseosa ingested during late fetal life. We tested the hypothesis that premature infants' lack of exposure to gastrointestinal (GI) BCFA is associated with their microbiota and risk for necrotizing enterocolitis (NEC) using a neonatal rat model. METHODS: Pups were collected one...
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