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Article

Longitudinal development of the gut microbiome and metabolome in preterm neonates with late onset sepsis and healthy controls

12 Jul 2017

Abstract excerpt

BACKGROUND: Late onset sepsis (LOS) in preterm infants is associated with considerable morbidity and mortality. While studies have implicated gut bacteria in the aetiology of the disease, functional analysis and mechanistic insights are generally lacking. We performed temporal bacterial (n = 613) and metabolomic (n = 63) profiling on extensively sampled stool from 7 infants with LOS and 28 matched healthy (no LOS...

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PMID: 28701177
DOI: 10.1186/s40168-017-0295-1

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