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Short-chain fatty acids—a key link between the gut microbiome and T-lymphocytes in neonates?

30 Apr 2025

Abstract excerpt

Infancy is a vulnerable and critical phase in the acquisition of the gut microbiome and the establishment of immune function. Short-chain fatty acids (SCFAs), such as acetate, propionate and butyrate, are compounds mostly produced by the microbiome through various metabolic pathways and play an indispensable role in connecting the microbiome and the adaptive immune system. This review aims to summarise recent...

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PMID: 40307498
DOI: 10.1038/s41390-025-04075-0

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