Article
Emergence of oseltamivir-resistant pandemic (H1N1) 2009 virus within 48 hours.
Emerging infectious diseases - 1 Oct 2010
Inoue Masafumi, Barkham Timothy, Leo Yee Sin, Chan Kwai Peng, Chow Angela, Wong Christopher W, Tze Chuen Lee Raphael, Maurer-Stroh Sebastian, Lin Raymond, Lin Cui
Abstract excerpt
An oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus evolved and emerged from zero to 52% of detectable virus within 48 hours of a patient's exposure to oseltamivir. Phylogenetic analysis and data gathered by pyrosequencing and cloning directly on clinical samples suggest that the muta...
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