Article
Non-stringent tissue-source requirements for BMP ligand expression in regulation of body size in Caenorhabditis elegans.
Genetics research - 1 Dec 2011
Savage-Dunn Cathy, Yu Ling, Gill Kwesi, Awan Muhammad, Fernando Thilini
Abstract excerpt
In Caenorhabditis elegans, the Bone Morphogenetic Protein (BMP)-related ligand Dpp- and BMP-like-1 (DBL-1) regulates body size by promoting the larval and adult growth of the large epidermal syncytium hyp7 without affecting cell division. This system provides an excellent model for dissecting the growth-promoting activities of BMP ligands, since in this context the growth and differentiation functions of DBL-1...
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