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Article

Prognostic significance and molecular associations of tumor growth pattern in colorectal cancer.

Annals of surgical oncology - 1 Jun 2012

Morikawa Teppei, Kuchiba Aya, Qian Zhi Rong, Mino-Kenudson Mari, Hornick Jason L, Yamauchi Mai, Imamura Yu, Liao Xiaoyun, Nishihara Reiko, Meyerhardt Jeffrey A, Fuchs Charles S, Ogino Shuji

Abstract excerpt

BACKGROUND: Infiltrative growth pattern at the tumor margin has been associated with shorter patient survival. However, little is known about the prognostic significance of tumor growth pattern, independent of tumoral molecular alterations and other histologic features. METHODS: Utilizing a database of 1139 colon and rectal cancer patients in two prospective cohort studies, histologic features including tumor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22189472
DOI: 10.1245/s10434-011-2174-5
PMCID: PMC3321113

Genes

BRAF
KRAS

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