Article
Risk factors for rectal cancer and methylenetetrahydrofolate reductase polymorphisms in a population in Northeast Thailand.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Promthet Supannee, Pientong Chamsai, Ekalaksananan Tipaya, Songserm Nopparat, Poomphakwaen Kirati, Chopjitt Peechanika, Wiangnon Surapon, Tokudome Shinkan
Abstract excerpt
BACKGROUND AND AIM: Polymorphisms in methylenetetrahydrofolate reductase (MTHFR) are known to be associated with predisposition for certain cancers. This study aimed to evaluate the effects of lifestyle factors, family history and genetic polymorphisms in MTHFR C677T and A1298C on rectal cancer risk and possible interactions with lifestyle factors in Northeast Thailand. METHODS: A hospital-based case-control...
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