Article
Strain construction and screening methods for a yeast histone H3/H4 mutant library.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Dai Junbiao, Boeke Jef D
Abstract excerpt
A mutant library consisting of hundreds of designed point and deletion mutants in the genes encoding Saccharomyces cerevisiae histones H3 and H4 is described. Incorporation of this library into a suitably engineered yeast strain (e.g., bearing a reporter of interest), and the validation of indivi...
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