Article
Therapy-related acute lymphoblastic leukemia is more frequent than previously recognized and has a poor prognosis.
Cancer - 15 Aug 2012
Abdulwahab Amal, Sykes Jenna, Kamel-Reid Suzanne, Chang Hong, Brandwein Joseph M
Abstract excerpt
BACKGROUND: Acute lymphoblastic leukemia (ALL) occurring in patients with a history of prior chemotherapy/radiotherapy exposure has been previously reported to be rare, accounting for <2.5% of ALL cases. METHODS: All cases of adult ALL with a history of prior cytotoxic or radiation therapy at a leukemia referral center over a 13-year period were analyzed. RESULTS: Twenty-three cases, representing 6.9% of all ALL...
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