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Therapy-Related Acute Lymphoblastic Leukemia Without 11q23 Abnormality

19 Dec 2009

Abstract excerpt

Therapy-related acute lymphoblastic leukemia (t-ALL) is a rare secondary leukemia following chemotherapy and/or radiotherapy for primary malignancies. Chromosomal 11q23 abnormality, frequently detected in therapy-related acute myeloid leukemia, is the most common cytogenetic alteration in t-ALL. However, t-ALL cases without 11q23 abnormality have been rarely described. We describe 6 adults with secondary t-ALL...

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PMID: 20023261
DOI: 10.1309/ajcpywc6aqc7bavj

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