Article
Estrogen receptor alpha gene polymorphisms and peak bone density in Chinese nuclear families.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2003
Qin Yue-Juan, Shen Hui, Huang Qi-Ren, Zhao Lan-Juan, Zhou Qi, Li Miao-Xin, He Jin-Wei, Mo Xiao-Yang, Lu Jing-Hui, Recker Robert R, Deng Hong-Wen
Abstract excerpt
PBD is an important determinant of osteoporotic fractures. Few studies were performed to search for genes underlying PBD variation in Chinese populations. We tested linkage and/or association of the estrogen receptor alpha gene polymorphism with PBD in 401 Chinese nuclear families. This study suggests the ER-alpha gene may have some minor effects on PBM variation in the Chinese population. Low peak bone density...
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