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Mitochondrial DNA sequence variation and risk of pancreatic cancer.

Cancer research - 1 Feb 2012

Lam Ernest T, Bracci Paige M, Holly Elizabeth A, Chu Catherine, Poon Annie, Wan Eunice, White Krystal, Kwok Pui-Yan, Pawlikowska Ludmila, Tranah Gregory J

Abstract excerpt

Although the mitochondrial genome exhibits high mutation rates, common mitochondrial DNA (mtDNA) variation has not been consistently associated with pancreatic cancer. Here, we comprehensively examined mitochondrial genomic variation by sequencing the mtDNA of participants (cases = 286, controls = 283) in a San Francisco Bay Area pancreatic cancer case-control study. Five common variants were associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22174369
DOI: 10.1158/0008-5472.CAN-11-1682
PMCID: PMC3271167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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