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mTOR Pathways in Cancer and Autophagy

12 Jan 2018

Abstract excerpt

TOR (target of rapamycin), an evolutionarily-conserved serine/threonine kinase, acts as a central regulator of cell growth, proliferation and survival in response to nutritional status, growth factor, and stress signals. It plays a crucial role in coordinating the balance between cell growth and cell death, depending on cellular conditions and needs. As such, TOR has been identified as a key modulator of...

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PMID: 29329237
DOI: 10.3390/cancers10010018

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