Article
Biomarkers of exposure and effect in Bulgarian petrochemical workers exposed to benzene.
Chemico-biological interactions - 30 May 2005
Garte Seymour, Popov Todor, Georgieva Tzveta, Bolognesi Claudia, Taioli Emanuela, Bertazzi Pieralberto, Farmer Peter, Merlo Domenico Franco
Abstract excerpt
Biomarkers of benzene exposure and effect were evaluated in 158 Bulgarian petrochemical workers and 50 matched controls. Air exposures to benzene averaged about 1.8 ppm, for workers and 0.02 ppm for controls. Urinary trans,trans-muconic acid, and S-phenylmuconic acid, showed dose response relationships with benzene air exposure. The dose response curve for DNA single strand breaks (SSB), but not for the...
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