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Article

Specific GATA factors act as conserved inducers of an endodermal-EMT.

Developmental cell - 13 Dec 2011

Campbell Kyra, Whissell Gavin, Franch-Marro Xavier, Batlle Eduard, Casanova Jordi

Abstract excerpt

The epithelial-to-mesenchymal transition (EMT) converts cells from static epithelial to migratory mesenchymal states (Hay, 1995). Here, we demonstrate that EMT in the Drosophila endoderm is dependent on the GATA-factor Serpent (Srp), and that Srp acts as a potent trigger for this transition when activated ectopically. We show that Srp affects endodermal-EMT through a downregulation of junctional dE-Cadherin...

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Identifiers

PMID: 22172671
DOI: 10.1016/j.devcel.2011.10.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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