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Article

Epiregulin (EREG) variation is associated with susceptibility to tuberculosis.

Genes and immunity - 1 Apr 2012

Thuong N T T, Hawn T R, Chau T T H, Bang N D, Yen N T B, Thwaites G E, Teo Y Y, Seielstad M, Hibberd M, Lan N T N, Caws M, Farrar J J, Dunstan S J

Abstract excerpt

Although host genetics influences susceptibility to Mycobacterium tuberculosis, the human genes regulating pathogenesis remain largely unknown. We used M. tuberculosis-stimulated macrophage gene expression profiling in conjunction with a case-control genetic association study to discover epiregul...

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Source

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Identifiers

PMID: 22170233
DOI: 10.1038/gene.2011.83
PMCID: PMC3684976

Genes

EREG
TLR2
MYD88
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22170233-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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