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Article

The IQ motif is crucial for Cav1.1 function.

Journal of biomedicine & biotechnology - 1 Jan 2011

Stroffekova Katarina

Abstract excerpt

Ca(2+)-dependent modulation via calmodulin, with consensus CaM-binding IQ motif playing a key role, has been documented for most high-voltage-activated Ca(2+) channels. The skeletal muscle Ca(v)1.1 also exhibits Ca(2+)-/CaM-dependent modulation. Here, whole-cell Ca(2+) current, Ca(2+) transient, and maximal, immobilization-resistant charge movement (Q(max)) recordings were obtained from cultured mouse myotubes,...

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Source

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Identifiers

PMID: 22162637
DOI: 10.1155/2011/504649
PMCID: PMC3228397

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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