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Article

Aberrant signaling pathways in pancreatic cancer: A two compartment view

12 Dec 2011

Abstract excerpt

Pancreatic cancer is a devastating disease with historically limited success in treatment and a poor prognosis. Pancreatic cancer appears to have a progressive pathway of development, initiating from well-described pancreatic intraepithelial neoplasia lesions and concluding with invasive carcinoma. These early lesions have been shown to harbor-specific alterations in signaling pathways that remain throughout this...

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PMID: 22162229
DOI: 10.1002/mc.20827

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