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The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells

1 Jan 2011

Abstract excerpt

Human MCF-7/6 breast cancer cells differ from their MCF-7/AZ counterparts by their invasiveness in a number of assays in vitro, such as invasion of MCF-7 spheroids into embryonic chick heart fragments or type I collagen gels. Comparative proteomic analysis of these two variants revealed an identical pattern, except for a 230 kDa protein present in the invasive MCF-7/6 variant, but hardly detectable in the...

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PMID: 22161839
DOI: 10.1387/ijdb.113336ld

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