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Article

A novel role for signal transducer and activator of transcription 5b (STAT5b) in β1-integrin-mediated human breast cancer cell migration

24 Jul 2009

Abstract excerpt

INTRODUCTION: Signal transducer and activator of transcription (STAT) 5b is a transcription factor involved in pro-proliferative and pro-survival signaling in a number of solid tumors, including breast cancer. The contribution of STAT5b to breast cancer cell motility has not been explored. This work aims to elucidate the role of STAT5b in breast cancer cell migration. METHODS: STAT5b was knocked down by using...

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PMID: 19630967
DOI: 10.1186/bcr2341

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