Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

5 Mar 2018

Abstract excerpt

Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease of the lungs that is currently the fourth leading cause of death worldwide. Genetic factors account for only a small amount of COPD risk, but epigenetic mechanisms, including DNA methylation, have the potential to mediate the interactions between an individual's genetics and environmental exposure. DNA methylation is highly cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Obstructive Pulmonary Disease (COPD) Research
Share to Epigenetics and DNA Methylation
Share to Neonatal Respiratory Health Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29527240
DOI: 10.1186/s13148-018-0464-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPDPMID 29527240Read ↗

Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function.Semantic proximity Read ↗

High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD phenotypes in human lung fibroblastsSemantic proximity Read ↗

DNA Methylation Is Globally Disrupted and Associated with Expression Changes in Chronic Obstructive Pulmonary Disease Small AirwaysSemantic proximity Read ↗

High‐resolution transcriptomic and epigenetic profiling identifies novel regulators of COPDSemantic proximity Read ↗

DNA Methylation of Fibroblast Phenotypes and Contributions to Lung Fibrosis.Semantic proximity Read ↗

Systemic and Airway Epigenetic Disruptions Are Associated with Health Status in COPDSemantic proximity Read ↗

Global DNA Methylation Pattern of Fibroblasts in Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

DNA methylation profiling in human lung tissue identifies genes associated with COPDSemantic proximity Read ↗

DNA methylation in pulmonary fibrosis and lung cancerSemantic proximity Read ↗

Interplay between genetics and epigenetics in lung fibrosisSemantic proximity Read ↗

DNA methylation profiling in peripheral lung tissues of smokers and patients with COPDSemantic proximity Read ↗

Lung cancer and its association with chronic obstructive pulmonary disease: update on nexus of epigeneticsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.