Article
A role for sister telomere cohesion in telomere elongation by telomerase.
Cell cycle (Georgetown, Tex.) - 1 Jan 2012
Houghtaling Benjamin R, Canudas Silvia, Smith Susan
Abstract excerpt
Telomere length homeostasis is achieved by a balance of telomere shortening caused by DNA replication and nucleolytic attack and telomere lengthening by telomerase. The importance of telomere length maintenance to human health is best illustrated by dyskeratosis congenita (DC) a disease of telomere shortening caused by mutations in telomerase subunits. DC patients suffer stem cell depletion and die of bone marrow...
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