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Article

Identifying quantitative trait loci via group-sparse multitask regression and feature selection: an imaging genetics study of the ADNI cohort.

Bioinformatics (Oxford, England) - 15 Jan 2012

Wang Hua, Nie Feiping, Huang Heng, Kim Sungeun, Nho Kwangsik, Risacher Shannon L, Saykin Andrew J, Shen Li

Abstract excerpt

MOTIVATION: Recent advances in high-throughput genotyping and brain imaging techniques enable new approaches to study the influence of genetic variation on brain structures and functions. Traditional association studies typically employ independent and pairwise univariate analysis, which treats single nucleotide polymorphisms (SNPs) and quantitative traits (QTs) as isolated units and ignores important underlying...

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Identifiers

PMID: 22155867
DOI: 10.1093/bioinformatics/btr649
PMCID: PMC3259438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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