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Article

The role of ALDH2 and ADH1B polymorphism in alcohol consumption and stroke in Han Chinese.

Human genomics - 1 Oct 2011

Yao Chung-Tay, Cheng Chun-An, Wang Hsu-Kun, Chiu Shao-Wen, Chen Yi-Chyan, Wang Ming-Fang, Yin Shih-Jiun, Peng Giia-Sheun

Abstract excerpt

The genes encoding the enzymes for metabolising alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2) - exhibit genetic polymorphism and ethnic variations. Although the ALDH2*2 variant allele has been widely accepted as protecting against the development of alcoholism in Asians, the association of the ADH1B*2 variant allele with drinking behaviour remains inconclusive. The goal of this study was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22155604
DOI: 10.1186/1479-7364-5-6-569
PMCID: PMC3525250

Genes

ALDH2

Provenance

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