Article
Can immune-related genotypes illuminate the immunopathogenesis of cytomegalovirus disease in human immunodeficiency virus-infected patients?
Human immunology - 1 Feb 2012
Affandi Jacquita S, Aghafar Zayd K A, Rodriguez Benigno, Lederman Michael M, Burrows Sally, Senitzer David, Price Patricia
Abstract excerpt
Most human immunodeficiency virus (HIV) patients are seropositive for cytomegalovirus (CMV) but a smaller proportion experience end-organ disease. This observation may reflect variations in genes affecting inflammatory and natural killer cell responses. DNA samples were collected from 240 HIV-infected patients followed at the University Hospitals/Case Medical Center (Cleveland, OH) between 1993 and 2008....
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