Article
Implementing non-invasive RHD genotyping on cell-free foetal DNA from maternal plasma: the Pavia experience.
Blood transfusion = Trasfusione del sangue - 1 Jan 2012
Sbarsi Ilaria, Isernia Paola, Montanari Laura, Badulli Carla, Martinetti Miryam, Salvaneschi Laura
Abstract excerpt
BACKGROUND: The occurrence of cell-free foetal DNA in maternal circulation opens new possibilities in non-invasive antenatal diagnosis. Real-time polymerase chain reaction (PCR) analysis is an useful approach to foetal RhD blood group determination, thus being important in the prevention of haemolytic disease of foetus and new-born (HDFN). STUDY DESIGN AND METHODS: Using real-time PCR assays we typed 20 samples...
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