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Article

Distinct structural changes underpin clinical phenotypes in patients with Gilles de la Tourette syndrome.

Brain : a journal of neurology - 1 Dec 2010

Worbe Yulia, Gerardin Emilie, Hartmann Andreas, Valabrégue Romain, Chupin Marie, Tremblay Léon, Vidailhet Marie, Colliot Olivier, Lehéricy Stéphane

Abstract excerpt

Gilles de la Tourette syndrome is a childhood-onset neurodevelopmental disorder characterized by tics that are often associated with psychiatric co-morbidities. The clinical heterogeneity of Gilles de la Tourette syndrome has been attributed to the disturbance of functionally distinct cortico-striato-thalamo-cortical circuits, but this remains to be demonstrated. The aim of this study was to determine the...

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Identifiers

PMID: 20959309
DOI: 10.1093/brain/awq293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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