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Molecular characterization of HIV type 1 isolates from untreated patients of Mumbai (Bombay), India, and detection of rare resistance mutations.

AIDS research and human retroviruses - 1 Sept 2004

Deshpande Alaka, Recordon-Pinson Patricia, Deshmukh Ranjana, Faure Muriel, Jauvin Valérie, Garrigue Isabelle, Lafon Marie-Edith, Fleury Hervé J

Abstract excerpt

The molecular characterization of HIV-1 isolates in drug-naive cases in the early stages of HIV disease was studied in 128 cases from Mumbai (Bombay), India. Subtype C was largely predominant followed by A-C intersubtype recombinants, one subtype A and one CRF01 AE. Compared to subtype B, subtype C exhibited an important polymorphism; the percentages of substitutions could reach more than 90%. Two isolates showed...

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PMID: 15585093
DOI: 10.1089/aid.2004.20.1032

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