Article
Investigation of baseline susceptibility to protease inhibitors in HIV-1 subtypes C, F, G and CRF02_AG.
Antiviral therapy - 1 Jan 2006
Abecasis Ana B, Deforche Koen, Bacheler Lee T, McKenna Paula, Carvalho Ana Patricia, Gomes Perpétua, Vandamme Anne-Mieke, Camacho Ricardo Jorge
Abstract excerpt
OBJECTIVE: To compare baseline susceptibility to protease inhibitors among HIV-1 isolates of subtypes C, F, G and CRF02_AG, and to identify polymorphisms that determine the differences in susceptibility. METHODS: A total of 42 samples of drug-naive patients infected with subtypes G (n=19), CRF02_AG (n = 10), F (n = 6) and C (n = 7) were phenotyped and genotyped with the Antivirogram and the ViroSeq 2.0 genotyping...
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