Investigation of baseline susceptibility to protease inhibitors in HIV-1 subtypes C, F, G and CRF02_AG.

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Article

Investigation of baseline susceptibility to protease inhibitors in HIV-1 subtypes C, F, G and CRF02_AG.

Antiviral therapy - 1 Jan 2006

Abecasis Ana B, Deforche Koen, Bacheler Lee T, McKenna Paula, Carvalho Ana Patricia, Gomes Perpétua, Vandamme Anne-Mieke, Camacho Ricardo Jorge

Abstract excerpt

OBJECTIVE: To compare baseline susceptibility to protease inhibitors among HIV-1 isolates of subtypes C, F, G and CRF02_AG, and to identify polymorphisms that determine the differences in susceptibility. METHODS: A total of 42 samples of drug-naive patients infected with subtypes G (n=19), CRF02_AG (n = 10), F (n = 6) and C (n = 7) were phenotyped and genotyped with the Antivirogram and the ViroSeq 2.0 genotyping...

Topics

Algorithms
Bayes Theorem
Drug Resistance, Viral
Genotype
HIV Infections
HIV Protease
HIV Protease Inhibitors
HIV-1
Humans
Indinavir
Models, Genetic
Nelfinavir
Phenotype
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 16964826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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