Article
Clinical parameters of inflammatory bowel disease in children do not correlate with four common polymorphisms of the transforming growth factor β1 gene.
Acta biochimica Polonica - 1 Jan 2011
Liberek Anna, Jakóbkiewicz-Banecka Joanna, Kloska Anna, Świderska Joanna, Kmieć Zbigniew, Łuczak Grażyna, Wierzbicki Piotr, Liberek Tomasz, Marek Krzysztof, Plata-Nazar Katarzyna, Sikorska-Wiśniewska Grażyna, Kamińska Barbara, Węgrzyn Grzegorz
Abstract excerpt
Transforming growth factor β1 (TGF-β1) is a cytokine affecting cell proliferation and development, which also has an immunomodulatory activity. Correlations between polymorphisms of the TGF-β1 gene and clinical parameters of inflammatory bowel disease (IBD) were reported previously in adults. Here, we tested whether such correlations occur in pediatric patients suffering from IBD. One hundred and four pediatric...
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