Article
Effects of TNFα, NOS3, MDR1 Gene Polymorphisms on Clinical Parameters, Prognosis and Survival of Multiple Myeloma Cases.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016
Basmaci C, Pehlivan M, Tomatir Ag, Sever T, Okan V, Yilmaz M, Oguzkan-Balci S, Pehlivan S
Abstract excerpt
It is not clear how gene polymorphisms affecting drugs can contributes totheir efficacy in multiple myeloma (MM). We here aimed to explore associations among gene polymorphisms of tumor necrosis factor alpha (TNFα), nitric oxide synthesis 3 (NOS3) and multi-drug resistance 1 (MDR1), clinical parameters, prognosis and survival in MM patients treated with VAD (vincristine-adriamycine-dexamethasone), MP...
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