Article
Quercetin-3-methyl ether suppresses proliferation of mouse epidermal JB6 P+ cells by targeting ERKs.
Carcinogenesis - 1 Feb 2012
Li Jixia, Mottamal Madhusoodanan, Li Haitao, Liu Kangdong, Zhu Feng, Cho Yong-Yeon, Sosa Carlos P, Zhou Keyuan, Bowden G Tim, Bode Ann M, Dong Zigang
Abstract excerpt
Chemoprevention has been acknowledged as an important and practical strategy for the management of skin cancer. Quercetin-3-methyl ether, a naturally occurring compound present in various plants, has potent anticancer-promoting activity. We identified this compound by in silico virtual screening of the Traditional Chinese Medicine Database using extracellular signal-regulated kinase 2 (ERK2) as the target...
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