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Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases

15 Nov 2011

Abstract excerpt

Ultraviolet (UV) irradiation is the leading factor in the development of skin cancer, prompting great interest in chemopreventive agents for this disease. In this study, we report the discovery of norathyriol, a plant-derived chemopreventive compound identified through an in silico virtual screening of the Chinese Medicine Library. Norathyriol is a metabolite of mangiferin found in mango, Hypericum elegans, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22084399
DOI: 10.1158/0008-5472.can-11-2596

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