Article
A mathematical model for the dynamics of cancer hepatocytes under therapeutic actions.
Journal of theoretical biology - 21 Mar 2012
Delitala Marcello, Lorenzi Tommaso
Abstract excerpt
This paper deals with the development of a mathematical model for the in vitro dynamics of malignant hepatocytes exposed to anti-cancer therapies. The model consists of a set of integro-differential equations describing the dynamics of tumor cells under the effects of mutation and competition phenomena, interactions with cytokines regulating cell proliferation as well as the action of cytotoxic drugs and targeted...
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