Article
ARID1A mutation associated with recurrence and shorter progression-free survival in atypical meningiomas.
Journal of cancer research and clinical oncology - 1 Jul 2023
Chaluts Danielle, Dullea Jonathan T, Ali Muhammad, Vasan Vikram, Devarajan Alex, Rutland John W, Gill Corey M, Ellis Ethan, Kinoshita Yayoi, McBride Russell B, Bederson Joshua, Donovan Michael, Sebra Robert, Umphlett Melissa, Shrivastava Raj K
Abstract excerpt
PURPOSE: The oncologic outcomes for atypical meningiomas can be poor. Generally, patients that have had a prior recurrence have a substantially elevated risk of a future recurrence. Additionally, certain tumor genomic profiles have been shown as markers of poor prognosis. We sought to characterize the genomic differences between primary and recurrent tumors as well as assess if those differences had implications...
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