Article
The role of the Epstein-Barr virus receptor CD21 in multiple sclerosis.
Journal of neuroimmunology - 18 Jan 2012
Toepfner Nicole, Cepok Sabine, Grummel Verena, Hemmer Bernhard
Abstract excerpt
Multiple Sclerosis (MS) is characterised by a chronic inflammation and demyelination of brain and spinal cord with a yet unknown aetiology. Based on multiple epidemiological and immunological studies, which suggest a role of Epstein-Barr virus (EBV) infection in the pathogenesis of MS, we investigated CD21 (CR2, complement receptor type 2), which serves as the EBV receptor. Serum concentrations of soluble CD21...
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