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Article

Polymorphism of interferon-gamma gene at position +874 and clinical characteristics of chronic hepatitis C.

Translational research : the journal of laboratory and clinical medicine - 1 Sept 2006

Dai Chia-Yen, Chuang Wan-Long, Hsieh Ming-Yen, Lee Li-Po, Hou Nai-Jen, Chen Shinn-Cherng, Lin Zu-Yau, Hsieh Ming-Yuh, Wang Liang-Yen, Tsai Jun-Fa, Chang Wen-Yu, Yu Ming-Lung

Abstract excerpt

A T-to-A polymorphic sequence at position +874 in the interferon (IFN)-gamma gene (+874 IFN-gamma) might be associated with disease susceptibilities. To investigate the influence of +874 IFN-gamma polymorphism on the hepatitis C virus (HCV) viral load and the severity of liver disease, the single nucleotide polymorphism (SNP) was determined in 302 histologically proved chronic hepatitis C (CHC) patients [M/F:...

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Identifiers

PMID: 16938650
DOI: 10.1016/j.trsl.2006.04.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Polymorphism of interferon-gamma gene at position +874 and clinical characteristics of chronic hepatitis C.PMID 16938650Read ↗

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The interferon-gamma (IFN-γ) +874T allele reduces the risk of hepatitis B infection in an Asian population.Semantic proximity Read ↗

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