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Article

Improving circulatory disturbance in transient abnormal myelopoiesis.

Journal of pediatric hematology/oncology - 1 May 2012

Koga Hiroshi, Miyako Kenichi, Suga Naohiro, Hidaka Tomoko, Takahashi Noboru

Abstract excerpt

Transient abnormal myelopoiesis (TAM) in neonates with Down syndrome (DS) is characterized by circulating blast cells in the blood. TAM usually resolves spontaneously, but several studies have associated this condition with early death, focusing on the development of effective treatments. We report the case of a neonate with DS who had TAM and novel GATA1 mutation. Although the patient eventually died of hepatic...

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Source

Identifiers

PMID: 22134612
DOI: 10.1097/MPH.0b013e31822bf608

Genes

GATA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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