Article
Tolerance and viral resistance after single-dose nevirapine with tenofovir and emtricitabine to prevent vertical transmission of HIV-1.
AIDS (London, England) - 27 Apr 2009
Arrivé Elise, Chaix Marie-Laure, Nerrienet Eric, Blanche Stéphane, Rouzioux Christine, Coffie Patrick A, Kruy Leang Sim, McIntyre James, Avit Divine, Srey Viseth Horm, Gray Glenda, N'Dri-Yoman Thérèse, Diallo Alpha, Ekouévi Didier K, Dabis François
Abstract excerpt
OBJECTIVE: Viral resistance occurs with high frequency after single-dose nevirapine. We aimed to evaluate the safety and resistance profiles of a combination of tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) in HIV-1-infected pregnant women and their newborns. DESIGN: An open-label phase I/II trial in Côte d'Ivoire, Cambodia and South Africa. METHODS: Women received antenatal zidovudine, intrapartum...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
