Article
Safety assessment of Lactobacillus plantarum JDM1 based on the complete genome.
International journal of food microbiology - 1 Feb 2012
Zhang Zhuo-Yang, Liu Chang, Zhu Yong-Zhang, Wei Yan-Xia, Tian Fei, Zhao Guo-Ping, Guo Xiao-Kui
Abstract excerpt
We performed a comprehensive safety assessment of a probiotic based on the whole genome sequence and corresponding phenotypes. This was performed on Lactobacillus plantarum JDM1, a widely used commercial probiotic strain in China. The minimal inhibitory concentrations (MICs) of sixteen antibiotics and the biogenic amine production of JDM1 were tested to supplement a traditional oral toxicity test. In total,...
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